<p>Fabrication of cRGD-modified reduction-sensitive nanocapsule via Pickering emulsion route to facilitate tumor-targeted delivery</p>
نویسندگان
چکیده
منابع مشابه
A Pickering Emulsion Route to Swimming Active Janus Colloids
The field of active colloids is attracting significant interest to both enable applications and allow investigations of new collective colloidal phenomena. One convenient active colloidal system that has been much studied is spherical Janus particles, where a hemispherical coating of platinum decomposes hydrogen peroxide to produce rapid motion. However, at present producing these active colloi...
متن کاملControlling Pickering Emulsion Destabilisation: A Route to Fabricating New Materials by Phase Inversion
The aim of this paper is to review the key findings about how particle-stabilised (or Pickering) emulsions respond to stress and break down. Over the last ten years, new insights have been gained into how particles attached to droplet (and bubble) surfaces alter the destabilisation mechanisms in emulsions. The conditions under which chemical demulsifiers displace, or detach, particles from the ...
متن کاملTumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA
RNAi technology is taking strong position among the key therapeutic modalities, with dozens of siRNA-based programs entering and successfully progressing through clinical stages of drug development. To further explore potentials of RNAi technology as therapeutics, we engineered and tested VEGFR2 siRNA molecules specifically targeted to tumors through covalently conjugated cyclo(Arg-Gly-Asp-d-Ph...
متن کاملMolecular imprinting of protein in Pickering emulsion.
A new strategy of molecular imprinting to prepare spherical hydrogels via water-in-oil Pickering emulsion polymerization was developed. The imprinted hydrogels exhibited fast adsorption kinetics and significant selectivity for the target protein.
متن کاملMaterial : Aging mechanism in model Pickering emulsion
The chemicals used for the NPs synthesis are TetraEthylOrthoSilicate (TEOS), l-Arginine, chloride acid 0.1M and ethanol. They were supplied by Aldrich and used as received. High-purity deionized water (18.2 M.cm) was produced using Millipore Milli-Q Gradient system. The synthesis follows the same protocol as in our previous work [1]. It is performed in a 2000 ml reactor thermostated with hot wa...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2019
ISSN: 1178-2013
DOI: 10.2147/ijn.s202063